🌱 OniX OnPoint: The Garden of Curiosities – Your Weekly Bloom of Breakthroughs

Exploring the Frontiers of Biomedical Science, Technology, and Surprising Discoveries

Welcome to this week’s edition of OniX OnPoint: The Garden of Curiosities, where we traverse the ever-evolving landscape of biomedical research, innovation, and scientific serendipity. From breakthrough therapies for osteoarthritis and malaria to the marvels of cellular rejuvenation, plastic upcycling, and brain organoid development, this issue curates the most intriguing advances and unexpected stories from the world of science and medicine. Whether you’re fascinated by the mechanics of life, the promise of new treatments, or the quirks of pharmaceutical policy, there’s something here to ignite your curiosity.

Table of Contents

1. Clinical efficacy of different therapeutic options for knee osteoarthritis: A network meta-analysis based on randomized clinical trials

2. In vivo screen of Plasmodium targets for mosquito-based malaria control

3. A biocompatible Lossen rearrangement in Escherichia coli

4. A single factor for safer cellular rejuvenation

5. Metabolic engineering: New-to-nature biocompatible chemistry for plastic waste upcycling

6. Novo Nordisk's Canadian Mistake

7. Morphodynamics of human early brain organoid development

8. A microRNA-based dynamic risk score for type 1 diabetes

9. Screening macrocyclic peptide libraries by yeast display allows control of selection process and affinity ranking

10. Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses

11. Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus

12. Timely TGFβ signalling inhibition induces notochord